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78. A patient with acute appendicitis presents with right lower quadrant pain, rebound tenderness, and fever. What is the critical clinical urgency in managing this condition?
A.
Oral antibiotics and observation.
✓
B.
Surgical appendectomy to prevent perforation and peritonitis.
✓
C.
Laxatives.
✓
D.
Pain medication only.
✓
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BS Nursing
Jun 6, 2026
77. A patient with a history of long-standing hypertension develops a hemorrhagic stroke. What is the technical primary pathophysiological cause of hemorrhagic stroke in this context?
A.
Thromboembolic event.
✓
B.
Rupture of a cerebral blood vessel (often due to weakened walls from chronic hypertension).
✓
C.
Vasospasm.
✓
D.
Global cerebral ischemia.
✓
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Jun 6, 2026
76. A patient with severe sepsis develops acute respiratory distress syndrome (ARDS). What is the technical primary pathophysiological change in ARDS?
A.
Bronchoconstriction.
✓
B.
Non-cardiogenic pulmonary edema due to increased alveolar-capillary membrane permeability.
✓
C.
Alveolar destruction.
✓
D.
Pulmonary fibrosis.
✓
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Jun 6, 2026
75. A patient with Type 2 Diabetes Mellitus develops hyperosmolar hyperglycemic state (HHS). What is the technical primary pathophysiological difference from diabetic ketoacidosis (DKA)?
A.
Presence of severe ketosis and acidosis.
✓
B.
Profound hyperglycemia and hyperosmolarity without significant ketosis.
✓
C.
Absence of dehydration.
✓
D.
Normal insulin levels.
✓
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Jun 6, 2026
74. A patient with severe anemia (Hb 5 g/dL) presents with pallor, fatigue, and dyspnea on exertion. What is the technical primary pathophysiological consequence of severe anemia?
A.
Increased oxygen-carrying capacity.
✓
B.
Decreased oxygen-carrying capacity of the blood, leading to tissue hypoxia.
✓
C.
Increased blood viscosity.
✓
D.
Enhanced immune response.
✓
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73. A patient with a suspected subarachnoid hemorrhage presents with sudden “thunderclap” headache, nuchal rigidity, and photophobia. What is the urgent clinical action required based on the likely pathophysiology?
A.
Oral analgesics.
✓
B.
Immediate neuroimaging to confirm hemorrhage and neurosurgical consultation.
✓
C.
Physical therapy.
✓
D.
Antihistamines.
✓
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72. A patient with a history of chronic kidney disease develops metabolic acidosis. What is the technical primary pathophysiological reason for this?
A.
Increased bicarbonate reabsorption.
✓
B.
Impaired renal excretion of acid and reduced bicarbonate regeneration.
✓
C.
Overproduction of lactic acid.
✓
D.
Excessive loss of CO2?.
✓
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Jun 6, 2026
71. A patient with Crohn’s disease develops intestinal strictures and fistulas. What is the technical pathophysiological process leading to these complications?
A.
Superficial mucosal inflammation.
✓
B.
Transmural inflammation and fibrosis.
✓
C.
Diverticular outpouchings.
✓
D.
Gastric acid erosion.
✓
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70. A patient with hyperthyroidism presents with weight loss, heat intolerance, tremors, and tachycardia. What is the technical primary pathophysiological cause?
A.
Decreased thyroid hormone production.
✓
B.
Excess thyroid hormone production, leading to a generalized hypermetabolic state.
✓
C.
Adrenal insufficiency.
✓
D.
Excess parathyroid hormone.
✓
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69. A patient with a history of deep vein thrombosis (DVT) is prescribed a direct oral anticoagulant (DOAC) like rivaroxaban. From a medicinal perspective, what is the technical pathophysiological mechanism of rivaroxaban?
A.
Inhibits Vitamin K epoxide reductase.
✓
B.
Directly inhibits Factor Xa.
✓
C.
Directly inhibits thrombin.
✓
D.
Binds to antithrombin III.
✓
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Jun 6, 2026
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