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CELL STRUCTURE & FUNCTION

100 questions found

Practice Questions

96. The architectural organization of the primary cell wall in plants reveals that cellulose microfibrils are synthesized by large, membrane-embedded protein complexes called

A. Ribosomal rosettes
B. Cellulose Synthase (CESA) complexes or terminal complexes
C. Dictyosome stacks
D. Spliceosome factories

CESA complexes are hexameric transmembrane rosette assemblies that extrude individual cellulose chains into the extracellular space.

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Jul 3, 2026

The cytoskeletal core forms an internal structural framework that preserves the basic architecture of the cell even when the outer membrane is disrupted.

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The mannose-6-phosphate tag acts as a molecular sorting signal that targets newly built hydrolytic enzymes to the lysosome.

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Auxin stimulates proton pumps to drive H+ into the cell wall; the resulting drop in pH activates expansins, loosening the wall to allow turgor-driven growth.

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Jul 3, 2026

100. The fundamental difference between the extracellular matrix (ECM) of animal tissues and the cell wall of plant tissues is that the animal ECM is dominated by

A. Rigid crystalline homopolysaccharides
B. Flexible fibrous proteins (like collagen and elastin) embedded in a glycosaminoglycan gel
C. Waterproof aromatic polymers like lignin
D. Highly ionized phosphate backbones

Animal cells secrete a protein-rich extracellular matrix (featuring collagen, fibronectin, and laminin) that provides structural support while remaining flexible, unlike the carbohydrate-dominated cell walls of plants.

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88. A genetic mutation disrupts the synthesis of clathrin proteins inside an animal cell line. Biochemically, this defect will lead to the selective arrest of

A. Simple passive diffusion of carbon dioxide gases
B. Receptor-mediated endocytosis and coated-vesicle budding
C. The synthesis of ribosomal subunits inside the nucleolus
D. The transport of electrons within the cristae

Clathrin is required to structuralize and coat invaginating pits during endocytosis; its absence blocks the internalization of specific ligands.

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Cellulase breaks down the cellulose microfibrils, and pectinase dissolves the middle lamella, releasing wall-free protoplasts.

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Jul 3, 2026

90. An in vitro biochemical assay demonstrates that the tonoplast of a plant cell contains an abundance of H+-ATPase pumps that actively transport protons from the cytosol into the vacuole. This active transport mechanism establishes a

A. Basic pH inside the vacuole relative to the cytoplasm
B. Highly acidic intra-vacuolar environment essential for activating hydrolytic enzymes
C. Hydrophobic core that excludes all dissolved mineral ions
D. Torsional strain that triggers the immediate destruction of plastids

Pumping protons into the central vacuole lowers its internal pH, creating an acidic environment that powers lysosome-like digestive enzymes.

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91. A patient presenting with muscle weakness and exercise intolerance is diagnosed with a mitochondrial myopathy caused by a point mutation in a mitochondrial tRNA gene. This metabolic disease affects both plant and animal cell lines because mitochondria

A. Are entirely dependent on nuclear genes for all their proteins
B. Possess their own independent, circular DNA and semi-autonomous translation machinery
C. Do not require ATP synthesis to survive
D. Are formed via the direct fusion of lysosomal vesicles

Mitochondria contain their own circular genome and ribosomes; mutations in their tRNA disrupt internal protein translation and ATP synthesis.

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92. A plant developmental biologist studies a mutant strain of Arabidopsis thaliana that lacks functional expansin proteins. Phenotypically, this mutation results in severe dwarfism because expansins are the mandatory wall proteins that

A. Catalyze the synthesis of secondary lignin complexes
B. Loosen the hydrogen bonds between cellulose microfibrils to permit turgor-driven wall extension
C. Replicate the circular genome of internal chloroplasts
D. Anchor the desmotubule inside the plasmodesmata pores

Expansins disrupt the non-covalent links between cellulose and hemicellulose, allowing turgor pressure to expand the primary cell wall.

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93. An animal cell line is engineered to completely block the expression of the protein vinculin, which is a structural component of focal adhesions. This genetic modification will directly impair the cell’s ability to

A. Form a functional cleavage furrow during mitotic division
B. Adhere to the extracellular matrix and migrate across surfaces
C. Synthesize cholesterol molecules inside the smooth ER
D. Route lysosomal enzymes from the Golgi to the lysosome

Vinculin helps anchor internal actin microfilaments to transmembrane integrins, a structural link required for cell-matrix adhesion and motility.

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94. The treatment of green algal plant cells with the drug monensin blocks the transport of newly synthesized matrix polysaccharides out of the Golgi apparatus. The immediate structural impact on the developing cell wall will be a severe reduction in the deposition of

A. Crystalline cellulose microfibrils
B. Pectins and hemicelluloses within the primary wall matrix
C. Insoluble mineralized lignin inside the secondary core
D. Suberin molecules along the outer Casparian strip

While cellulose is built directly at the plasma membrane, matrix pectins and hemicelluloses are processed in the Golgi and shipped out via vesicles.

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Jul 3, 2026

The symplast is the continuous web of living cytoplasm interconnected by plasmodesmata, allowing signaling molecules to travel throughout the plant.

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80. The dynamic structural component that lines the inner surface of the nuclear envelope in animal cells to provide mechanical support and anchor chromatin is the

A. Actin cortex
B. Nuclear lamina (composed of intermediate filaments)
C. Cell wall matrix
D. Cortical microtubule ring

The nuclear lamina is an interlaced protein mesh made of lamins that supports the nuclear envelope and organizes internal chromatin.

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Jul 3, 2026

81. The direct cellular source of the energy currency molecule ATP required to run active transport pumps across the plasma membrane of an animal cell is

A. Photophosphorylation in chloroplasts
B. Oxidative phosphorylation in mitochondria
C. Hydrolysis of structural cellulose
D. Fusion of lysosomal vesicles

Mitochondria harvest chemical energy from food molecules via cellular respiration, producing ATP to power energy-dependent cell processes.

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Jul 3, 2026

82. The fundamental difference in the structural response of a plant cell versus an animal cell to a highly hypertonic external fluid environment is that

A. The plant cell bursts while the animal cell stays stable
B. The plant cell experiences plasmolysis while keeping its outer shape, whereas the animal cell shrinks completely
C. The plant cell undergoes immediate binary fission
D. The animal cell synthesizes a protective cellulose wall

The plant cell's protoplast shrinks inward while its rigid wall maintains the outer cell shape; the wall-less animal cell shrivels up completely.

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Integrins are transmembrane receptor proteins that link the intracellular cytoskeleton to the extracellular matrix, facilitating cell signaling.

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84. The primary biochemical function of the carbohydrate component that forms the outer glycocalyx coating of animal cells is

A. Serving as a template for DNA replication
B. Cell-to-cell recognition and immune system identification
C. Driving the electron transport chain
D. Storing high-density triacylglycerol reserves

The branched sugar chains of the glycocalyx act as molecular tags, enabling the immune system to recognize self cells and coordinate interactions.

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Jul 3, 2026

85. The biochemical nature of the enzyme catalase, which resides inside the peroxisomes of both plant and animal cells, is a

A. Structural lipid matrix
B. Conjugated globular protein (enzyme)
C. Unbranched homopolysaccharide
D. Single-stranded ribozyme

Catalase is a tetrameric protein enzyme containing four heme groups, optimized to break down hydrogen peroxide into water and oxygen.

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Jul 3, 2026
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