Practice Questions

Tay-Sachs is a lysosomal storage disorder where the inability to break down membrane gangliosides leads to toxic buildup in neurons.

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Lectins are specialized proteins that recognize and bind specific carbohydrate structures, facilitating cell-to-cell contact.

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38. The enzyme known as telomerase contains a functional RNA sequence bound to a catalytic protein, making it a

A. Glycoprotein enzyme
B. Ribonucleoprotein enzyme
C. Phosphoprotein complex
D. Chromoprotein system

Telomerase requires its intrinsic RNA component to serve as a matching template for the synthesis of telomeric DNA chromosome ends.

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37. The molecule known as ceruloplasmin, which carries copper ions in the blood plasma, belongs to the class of

A. Lipoproteins
B. Metalloproteins
C. Nucleoproteins
D. Glycolipids

Ceruloplasmin is a specialized transport protein and enzyme that binds copper ions tightly, making it a conjugated metalloprotein.

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36. The functional consequence of a bacterial cell producing capsule-associated glycoproteins is enhanced

A. Resistance against host phagocytosis
B. Susceptibility to penicillin antibiotics
C. Rate of binary fission division
D. Ability to fix atmospheric nitrogen

Scurrying pathogens use hydrophilic, slippery glycoprotein capsules to hide their surface markers and evade immune cell engulfment.

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As VLDL unloads triacylglycerols into adipose tissues via lipoprotein lipase, it becomes denser and transforms into cholesterol-rich LDL.

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34. The major conjugated molecule present in the extracellular matrix of cartilage that provides compressive strength and elasticity is a

A. Nucleoprotein complex
B. Proteoglycan aggregate
C. Lipopolysaccharide sheet
D. Pure fibrous elastin

Proteoglycans form large aggregates with hyaluronic acid in cartilage, trapping water molecules to resist mechanical compression.

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33. An increase in the concentration of blood plasma lipoproteins containing the highest percentage of proteins by weight results in

A. Enhanced removal of arterial cholesterol plaques
B. Rapid acceleration of plaque formation in coronary vessels
C. Fatal clotting of the pulmonary vein pathways
D. Decreased transport of fat-soluble vitamins

High-density lipoproteins (HDL) have the highest protein-to-lipid ratio and act to clear excess cholesterol from the circulatory pathways.

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32. The structural organization of the tobacco mosaic virus (TMV) represents a classic example of a conjugated

A. Glycolipid
B. Nucleoprotein
C. Lipoprotein
D. Metalloprotein

TMV consists of a single strand of genomic RNA wrapped in a helical coat of capsomere proteins, forming a pure nucleoprotein.

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31. The function of chylomicrons synthesized by the mucosal cells of the small intestine is to transport

A. Dietary lipids via the lymphatic and circulatory systems
B. Nuclear DNA from enterocytes to leukocytes
C. Glycogen directly to the skeletal muscle tissues
D. Heavy metal ions out of the digestive tract

Chylomicrons are large lipoproteins that absorb and transport dietary triacylglycerols and cholesterol from the intestines into lacteals.

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