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BIO NMDCAT Factors that Affect the Rate of Enzyme Reactions
mintcream-chough-797767.hostingersite.com July 11, 2026

A decrease in pH far below the optimum value causes reduced enzyme activity because

A. The substrate completely disappears
B. Ionic and hydrogen bonds maintaining enzyme structure become disrupted
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C. The activation energy becomes negative
D. Product concentration becomes zero

📝 Explanation

Extreme pH alters the ionization of amino acid side chains and disrupts the interactions maintaining the enzyme's tertiary structure.

📖 Additional Information

  • The substrate completely disappears
  • Ionic and hydrogen bonds maintaining enzyme structure become disrupted
  • The activation energy becomes negative
  • Product concentration becomes zero

Extreme pH alters the ionization of amino acid side chains and disrupts the interactions maintaining the enzyme's tertiary structure.

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